Grant Hill
The third overall pick in the 1994 NBA draft, Grant Hill was widely regarded as one of the game’s best all-around players. Multiple ankle surgeries, however, put an end to that dream.
Hill went on to play 200 games or so over the course of seven years, despite chronic ankle issues caused by his numerous surgeries. It had been a bad downhill spiral for him, given that he had once been considered one of the best.
Bo Jackson
Bo Jackson is so well-known that he appears in almost every discussion of the best athletes in the world. He was the first athlete to be named to the MLB and NFL All-Star teams, and he also competed in track and field.
He went on to achieve many great feats in baseball and football, cementing his status as a legend, but in 1990, his hip was dislocated in a freak injury during a football game. After that, he only played a few more seasons due to his injury, which he never fully recovered from.